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About Topoisomerases
You may wonder about the structure of DNA such as is it tangled or does it become stressed? Well the answer is yes but there a protein that relaxes and untangles DNA,it is called Topoisomerases.Topoisomerases is a protein that untangles and relax DNA.

Function
Topoisomerases wraps itself around DNA and makes a cut in one strand. While holding that damaged area, the enzyme allows the helix to spin, relaxing any tangled or untangled. After DNA relaxed,topoisomerase reconnects the broken strand, then returning DNA double helix back.

Structural Properties
Topoisomerases is mostly apla heliex,it also has beta sheet's and that concect each other. So there primary and secondary and 3rd level and maybe the 4th levl of structure